Biomedical Technology

PenTide Therapeutics Limited

🚫 No Website Found 🏢 HKSTP Source
52 Potential

Decision Maker

Dr. Yanfeng WANG
yfwang@pentidetherapeutics.com
98508201
Room 04, CCC, 1/F, Building 9W and Room 625, 6/F, Building 17W, No. 9 and No. 17 Science Park West Avenue, Hong Kong Science Park, Pak Shek Kok, N.T.
Raw Description
PenTide Therapeutics Limited is a pre-clinical stage biotech company founded in Hong Kong in 2021. We strive to develop next-generation drug delivery technologies and provide novel therapeutics for unmet medical needs. | We are focused on the development of innovative drug delivery systems leveraging on our proprietary technologies in: i) improving treatment effects of existing drugs via 505(b)(2) registration; ii) cell-penetrating peptide-based delivery for antibody, non-viral vaccine, or gene therapy; and iii) brain targeted delivery of peptide drugs to treat Alzheimer’s and Parkinson’s Diseases. | Our differentiated product pipeline will fulfil unmet medical needs and provide improved convenience and compliance. | Our proprietary technologies for drug delivery enhancement enable non-invasive, fast and sustained drug delivery from small molecules to biologics. | Description | Our Company focuses on the development of innovative drug delivery systems || Product | 1. Intranasal Semaglutide | 2. Palonosetron Intranasal Spray

Strategic Analysis

Executive Brief

PenTide Therapeutics is a Hong Kong-based biotech firm specializing in advanced drug delivery systems, specifically focused on bypassing the blood-brain barrier (BBB) via intranasal routes and cell-penetrating peptides. Their R&D centers on the delivery of peptides and biologics for neurodegenerative diseases (Alzheimer’s, Parkinson’s) and metabolic health (Semaglutide), requiring highly sensitive analytical validation and bio-inert environments.

Strategic Fit & Lead Score

Lead Score: 52 (40-59: General Research / Engineering)

Why this Score? While PenTide is a drug development company, their technical bottleneck lies in the characterization and validation of drug delivery. To prove their peptides reach the brain or maintain specific concentrations in vivo, they require ultra-sensitive electrochemical sensors that do not foul in biological fluids. 6C’s Boron Doped Diamond (BDD) is the premier material for this. Additionally, as they scale, pharmaceutical wastewater treatment (AOP) using BDD electrodes becomes a regulatory necessity.

6C Solutions Proposal

Application Area 6C Solution Technical Value Prop
Pharmacokinetic Sensing BDD Electrodes Wide Electrochemical Window: Enables detection of therapeutic peptides and neurotransmitters (Dopamine/Serotonin) at concentrations < 10nM with zero surface fouling.
In-Vivo Neuro-Probes Custom BDD Coating Bio-compatibility: Diamond is chemically inert and non-toxic. Coating micro-probes allows for long-term monitoring of brain chemistry in Alzheimer’s/Parkinson’s models without immune rejection.
Analytical Hardware SCD Optical Windows Ultra-Pure Spectroscopy: Single Crystal Diamond (SCD) windows allow for high-throughput IR/Raman analysis of peptide folding and stability with Ra < 1nm roughness.
Cleanroom Sanitation BDD Electrochemical Cells On-site Ozone Generation: BDD electrodes can generate high concentrations of O3 or hydroxyl radicals from water to sanitize drug-handling equipment without chemical residues.
Microfluidics Diamond-on-Silicon Wafers Non-stick Surfaces: Direct diamond coating of microfluidic channels prevents peptide "sticking" (adsorption), a common failure mode in peptide delivery R&D.

Engagement Hooks

  • Technical Question: "As you refine your brain-targeted delivery for Alzheimer’s, how are you overcoming the signal-to-noise limitations and electrode fouling inherent in standard carbon or gold sensors when measuring peptide concentrations in the cerebrospinal fluid?"
  • Value Statement: "6C can provide PenTide with Boron Doped Diamond (BDD) sensing platforms that offer the world’s widest electrochemical window, enabling the real-time detection of metabolic and neuro-peptides that are invisible to traditional analytical hardware."