Biomedical Technology

GLOAS Limited

🌍 Official Website 🏢 HKSTP Source
62 Potential

Decision Maker

Dr. Thomas Leon
thomas.leon@gloas.org
63008580
Lab Bench 10d-f, Unit 708-716, 7/F, 17W & Cubicle 10 (S72-73, S75-76), 6/F, Building 17W No. 17 Science Park West Avenue Hong Kong Science Park,Pak Shek Kok,N.T.
Raw Description
Our mission is to revolutionise drug and therapeutic discovery and development, provide a novel and affordable solution for medical treatment, patient stratification and disease diagnostics for rare diseases in newborns. | We have noticed a lack of effective treatments for these conditions and an urgent need for human organ proxies in vitro for disease modelling, biomarker, drug and therapeutic discovery. | To address these challenges, we will provide state-of-the-art and first-in-class human disease organoids for personalised precision medicine, regenerative medicine and preventive care for rare newborn diseases. Our organoid platform marks the beginning of the deployment of a novel and affordable solution for medical treatment, patient stratification and disease diagnostics. This platform is poised to make a significant impact in reducing mortality rate, saving billions of dollars in healthcare costs and improving the quality of life for individuals. | Description | GLOAS (Gut Liver Organoid Advance Science) Limited – a pioneer in revolutionising drug and therapeutic discovery and development || Product | Our human iPSC-derived organoids provide an immediate solution to the problem. | An organoid is a miniaturised and simplified version of an organ produced in vitro in three dimensions, demonstrating realistic micro-anatomy and resembling a near-native mini-organ in a dish. They are derived from tissue stem cells, embryonic stem cells, or induced pluripotent stem cells (iPSCs), which can self-organise in three-dimensional culture due to their self-renewal and differentiation capabilities. Scientists use organoids to study diseases and treatments in the laboratory. | GLOAS offers state-of-the-art technology platforms, including patient and normal human induced pluripotent stem cells (hIPSCs); first-generation patient and normal hIPSC-derived human organoids with one cell type (human organoids 1.0); second-generation advanced patient and normal human organoids with multiple cell types (human organoids 2.0); tissue hydrogel; and fabricated human bile ducts, all aimed at revolutionising the discovery and development of drugs and therapeutics for neonatal rare diseases. | Follow Us

Strategic Analysis

Executive Brief

GLOAS (Gut Liver Organoid Advance Science) Limited is a biotech pioneer specializing in the development of human induced pluripotent stem cell (hIPSC)-derived organoids. They produce 3D miniaturized human organ proxies (Gut/Liver) to revolutionize drug discovery and disease modeling for rare neonatal conditions. Their technical focus lies in complex 3D cell culture, tissue hydrogels, and the fabrication of functional biological structures like bile ducts.

Strategic Fit & Lead Score

Lead Score: 62 (Adjacent Tech / Strong Potential)

Why this Score? While GLOAS is a biology-centric firm, their "Human Organoid 2.0" and "Fabricated Bile Duct" products require advanced micro-environments and real-time sensing. 6C’s diamond technology addresses the primary bottlenecks in high-fidelity bio-sensing: electrode fouling, signal-to-noise ratios in complex media, and biocompatible substrate cooling for high-resolution imaging.

6C Solutions Proposal

Application Area 6C Solution Technical Value Prop
Real-time Metabolite Sensing BDD (Boron Doped Diamond) Electrodes BDD offers the widest electrochemical potential window and extreme resistance to "bio-fouling." This allows GLOAS to monitor pH, oxygen, and metabolic markers in organoid cultures for weeks without sensor drift.
High-Res Optical Imaging SCD (Single Crystal) Windows For "organoid-on-a-chip" applications, SCD provides 99% transparency from UV to Far-IR. Its high thermal conductivity prevents localized laser heating during long-term confocal or Raman microscopy.
Bio-Scaffold Engineering Diamond-Coated Micro-Scaffolds CVD Diamond is chemically inert and biocompatible. Coating synthetic scaffolds or bile duct frames can improve structural rigidity and provide a "cell-friendly" surface that resists protein denaturation.
Incubator Thermal Mgmt PCD (Polycrystalline) Heat Spreaders High-throughput screening (HTS) plates generate localized heat. Integrating PCD spreaders ensures ± 0.1°C temperature uniformity across a 96-well organoid plate, critical for sensitive iPSC differentiation.
Custom R&D Systems Desktop MPCVD Reactor Enables GLOAS to experiment with functionalizing diamond surfaces (e.g., oxygen or hydrogen termination) to control protein adsorption and cell adhesion directly in their lab.

Engagement Hooks

  • Technical Question: "How does GLOAS currently manage electrode fouling and signal degradation when performing long-term electrochemical monitoring of organoid metabolic activity in protein-rich media?"
  • Value Statement: "6C can help GLOAS transition from 'end-point' analysis to continuous, real-time data capture by providing Boron-Doped Diamond sensors that remain stable in biological environments for the entire duration of a 3D culture cycle."